CFL Picks and Parlays Today: Best Bets and Props for Sept. 25

Written By Jason Green | Published at September 25, 2026

CFL picks and parlays for game between Saskatchewan and BC. The Lions have won six of seven games and beat the Roughriders in Week 12. — Jun 7, 2025; Vancouver, British Columbia, Canada; BC Lions quarterback Nathan Rourke (12) looks to pass the ball during the second half against the Edmonton Elks at BC Place Stadium. Mandatory Credit: Anne-Marie Sorvin-Imagn Images

In a big West Division matchup on Friday night, the BC Lions host the Saskatchewan Roughriders. We will show you the best CFL picks and parlays for the game, along with prop bets for this division clash.

If you are new to parlays, check out our parlay betting guide.

CFL Picks and Parlays Today

Sports Interaction Sportsbook has the Lions as 3.5-point favorites with the total sitting at 62.5.

Saskatchewan is in second place in the West Division (8-5) and one game up on BC (7-6), whom they beat at home in Week 2 but lost on the road in Week 12. After a bad start, the Lions are 6-1 in their last seven games and back in the playoff picture. They scored a season-high 48 points in their last game, and on the other side of the coin, the Roughriders scored a season-low six points in their last game.

Saskatchewan is coming off a much-needed bye after laying an egg on offense in their last game with only six points. However, more rest will not mean more points, as BC will stay hot, win, and cover.

Best Bet: BC Lions to win and cover: (-3.5, Sports Interaction)

Saskatchewan vs. BC Parlay #1: Lions Prevail Again

BC to win and cover: BC is hot, winners of six of their last seven games, including a win over Saskatchewan, and in their last game they were impressive in a 48-29 win over a Montreal team that has the best record in the CFL. The Roughriders are coming off a bad 19-6 loss to Winnipeg, and they have lost their last three road games.
Under 62.5 points – While the Lions lit it up in their last game, scoring 48 points, this one will be a lower-scoring affair. When these teams met last, the total went Under. Saskatchewan scored only six points in their last game, and the total has gone Under in four of their last five games.

The odds for this simple spread/total parlay are +278, so a $100 bet would pay $378, for a $278 profit.

CFL parlay: BC to win and cover and Under 62.5 points - (+278, Sports Interaction)

Saskatchewan vs. BC Parlay #2: Expect Low-Scoring First Half

Under 30.5 points in first half: Saskatchewan only scored six points total in their last game, and when these two teams met in Week 2 at Saskatchewan, they totaled 27 points in the first half and totaled 19 points in Week 12 at BC.
BC to have the lead after the first quarter: They led in the first quarter in the last game facing the Roughriders, who have not led in the first quarter in their last three road games.

The odds for this parlay are +238, so a $100 bet would pay $338, for a $238 profit.

CFL parlay: Under 30.5 points in the first half and BC to lead after first quarter - (+238, Betway)

CFL Player Prop Bets to Consider

CFL player prop bet #1: Lions' Zander Horvath to score a TD - (-250, Sports Interaction)

If there were one player prop bet I would jump on, it would be this one, even if the odds aren't very enticing. Lions’ running back Horvath leads the CFL with 16 TDs, and he's been a touchdown machine lately.

In his last three games, he has rumbled to the back of the end zone seven times, and he also had a TD run in the Week 12 win over Saskatchewan.

CFL player prop bet #1: Lions' Keon Hatcher to score a TD - (-110, Sports Interaction)

Ok, Hatcher has only had five scores this season, but he has one in each of the last two games. He leads the Lions in receiving yards and will be targeted in this game.