NRFI & YRFI Odds: MLB No Runs & Yes Runs First Inning Betting For Thursday, April 4
Written By Mo Nuwwarah | Last Updated at August 27, 2025
If you're looking to bet NRFI (or YRFI) in MLB odds, TheLines has you covered. Here, we'll collect the best No Run First Inning odds from a variety of betting sites to aid your NRFI odds line shopping. Read on to find the best NRFI odds from Thursday, April 4.
Today's NRFI options include several games involving weak lineups. Some strong pitchers will also take the mound in Guardians at Twins, with cold and wind potentially helping keep the ball in the park. Want to learn more? Explore our "What is NRFI?" page.
Game Best NRFI Odds Best YRFI Odds Tigers at Mets (G2) Pirates at Nationals Guardians at Twins Marlins at Cardinals White Sox at Royals
Handicapping NRFI & YRFI Odds For April 4
Which games have a decent setup for NRFI odds, and which ones might be more attractive for YRFI bettors? Before you start looking, be sure to consult our NRFI guide for general strategy:
Marlins At Cardinals
Bettors might see Lance Lynn and Ryan Weathers and immediately think YRFI. Offense may be harder to come by than some expect, though.
Busch Stadium is favorable for pitchers, with a 99 overall park factor and just a 90 home-run factor, meaning they're suppressed by about 10%.
And Weathers has come out of the gate throwing hard, clocking a 97 mph average heater in his 2024 debut. That's almost a full 2 mph harder than he threw last season. And he got a decent amount of whiffs with a swinging strike rate of 11.7%. He might be an intriguing breakout candidate if he keeps that up.
Lynn enjoyed a decent debut back in red despite a brutal matchup with the Dodgers offense. He's looking to bounce back from a career-worst season, and the projections think he'll turn in a league-average performance. And he gets to face a putrid Miami offense, one projected to be among the league's weaker units, and that ranks 28th in the early going.
Cold weather (48 degrees) also helps the NRFI odds here.
Guardians At Twins
Tanner Bibee and Cy Young odds hopeful Pablo Lopez meet in Minnesota. With a low total and two solid arms on the bump, this one looks set up to be low scoring.
Indeed, a 47-degree forecast will help keep the ball in the park.
But Minnesota isn't the worst park for offense and has a home-run factor of 104.
Also, the tops of these lineups are fairly strong. Cleveland features several solid lefties, including the powerful Josh Naylor and Jose Ramirez. The lefty-heavy top of the lineup matches up well against Lopez, who has started to show decent-sized platoon splits thanks to leaning on his new sweeper. He was about a run worse with the platoon disadvantage last season.
Cleveland's offense has started off hot in general, too, leading MLB in wRC+ in the very early going.
Minnesota has not been as fortunate so far, but this offense does project to be around the top 10. Losing Royce Lewis certainly hurts, but Bibee had a rough first start with more walks than strikeouts and may still be finding his footing. His velocity was also down more than a full mph compared to last season, so he may need some time to get going.
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