Best NBA Bets Today: Picks and Predictions for Nov. 5

Written By Nick Crain | Last Updated at November 5, 2025

The NBA season rolls on with a loaded Wednesday slate, offering several strong value spots for bettors on sports betting apps, and high-value sportsbook promotions to further enhance our best NBA bets today.

From underdogs with momentum to favorites facing short-handed opponents, these are five of the best NBA bets today to consider.

Brooklyn Nets ML (+222) vs. Pacers

Odds via BetMGM

The Nets have gotten off to a 0-7 start to the season, but catching them at +222 against an inconsistent Pacers team offers real value. Brooklyn has players who can fill up the scoring column, so if the defense can hold its own, there's no question that Brooklyn can win this game.

At 1-6, the Pacers haven't been much better this season and have faced significant injuries. This should be a close game, which is why the plus odds for the Nets are so intriguing. Make sure to take advantage of BetMGM's latest promo codes for even more value on this underdog play.

Minnesota Timberwolves +5.5 (-110) vs Knicks

Odds via bet365

Minnesota’s size and physicality make it a tough matchup for a Knicks team that relies on grinding games out. Furthermore, Anthony Edward is listed as questionable to make his return from injury today, so getting this line now could pay off.

The Knicks are a real contender this season, but clearly have flaws and have struggled at times early in the season. They're the favorite today, but the Wolves should be able to keep it very close and cover the spread.

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Houston Rockets -7.5 (-110) vs Grizzlies

Odds via BetMGM

Memphis remains one of the most depleted teams in the league, and Houston has quietly found a rhythm behind Alperen Sengun and Kevin Durant. The Rockets’ defense is among the best in the league, and this looks like another game where they can control tempo and win comfortably on the road.

Ja Morant is making headlines for being suspended for conduct detrimental to the team, so the vibes around the Grizzlies locker room are interesting. Combine that with the fact that the Rockets are a much better team and this could very easily be a double-digit Houston win.

San Antonio Spurs ML (+118) vs Lakers

Odds via Caesars Sportsbook

The Lakers are a veteran group with a ton of star talent, while the young Spurs are beginning to find their groove as the young surprise team of the season. Victor Wembanyama’s impact is growing as he makes an early MVP case, and San Antonio’s depth should allow them to keep the pace high and steal one in Los Angeles.

Especially given Wembanyama is coming off the worst game of his season, he'll look to have a huge night against a mediocre Lakers frontcourt. Even then, Los Angeles has dynamic scorers who will be tough to contain defensively, which is why this will be a close contest, but I have the Spurs coming out on top.

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Portland Trail Blazers +5.5 (-110) vs. Thunder

Odds via bet365

Oklahoma City is red-hot with an 8-0 start, but the Thunder will be on the second night of a road back-to-back today. Combine that with the number of injuries the team has, including Jalen Williams still sidelined, and the Blazers have a real shot to keep this game close, or even win.

Portland has a solid roster, with a blend of young prospects and proven veterans. Led by a strong defense, the Blazers should be able to keep this game within a possession or two and cover the spread.

As the early NBA season continues to take shape, there’s plenty of value on both sides of the spread for bettors willing to dig in. Be sure to shop lines across the top sports betting apps and take advantage of the latest sportsbook promotions to maximize your edge when locking in the best NBA bets today.

Odds as of 6:00 a.m. ET on Nov. 5