Best College Basketball Picks Today (Nov. 24)

Written By Nick Crain | Published at November 24, 2025
Nov 18, 2025; New York, New York, USA; Kansas Jayhawks head coach Bill Self looks on during the second half against the Duke Blue Devils at Madison Square Garden. Mandatory Credit: Vincent Carchietta-Imagn Images

Monday’s college basketball slate features a packed schedule of non-conference matchups, which usually leads to a mix of huge spreads and a handful of competitive games that offer real betting value. It’s a great night to take advantage of sportsbook promotions and compare prices across the top sports betting apps, especially with several ranked teams in action and some tricky road environments on the board.

Below are seven of the best college basketball bets today with clean lines and strong matchup angles.

Oregon State -3.5 (-110) vs UMass

Odds via BetMGM

Oregon State has the defensive edge and should be able to dictate tempo at home, where they’ve historically been much stronger. UMass has shown struggles in the halfcourt on the offensive side of the ball, which plays directly into the Beavers’ physical style.

Baylor -3.5 (-110) vs Creighton

Odds via bet365

Baylor’s guard play and spacing give them the offensive versatility to attack Creighton’s defense. The Bluejays are dangerous but lack the perimeter depth Baylor brings to the table, making this a favorable matchup for the Bears at home, where they're very hard to beat.

Boise State ML (+222) vs USC

Odds via Caesars Sportsbook

ExtraMile Arena is a tough place to play, and Boise State's defensive intensity can force opponents into long scoring droughts. USC has the talent edge and is 4-0, but this team has certainly shown some vulnerabilities, making Boise State a strong value play at plus money on their home floor at these odds.

Kansas -4.5 (-115) at Notre Dame

Odds via BetMGM

Kansas has the clear talent advantage and should win individual matchups across the board, especially given the Jayhawks have already played teams better than Notre Dame and have matched up well. With more scoring balance and better rim protection, Kansas is positioned to cover the short number.

St. John’s ML (+130) at Iowa State

Odds via bet365

St. John’s has the athleticism and guard play to hang with Iowa State, especially if they can speed up the pace and turn this into a transition-heavy game. Their ability to pressure the ball and create easy points gives them real upset potential on the road, given their discipline.

Illinois -32 (-110) vs UTRGV

Odds via BetMGM

Illinois has the size, athleticism, and depth to pull away quickly in this matchup, and UT Rio Grande Valley has struggled to stay competitive against high-major programs. Blowout potential is high here, and Illinois should overwhelm them in every phase. This one should really come down to whether the players at the end of the bench can maintain the lead late.

Michigan -6.5 (-110) at San Diego State

Odds via Caesars Sportsbook

Michigan’s frontcourt advantage and defensive rebounding should limit SDSU’s second-chance points, which is critical against a physical Aztecs team. Michigan’s more consistent scoring gives the Wolverines a slight edge in what should be a hard-fought road game.

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Not only are these all great bets, but there's additional value in parlaying the best three. Building a three-leg parlay including Kansas (-4.5), Baylor (-3.5) and Oregon State (-3.5), these slight favorites combined for a +581 line (via Caesars Sportsbook).

With so many non-conference games on the board, it’s important to find matchups where talent gaps, efficiency trends or home-court advantages create real value. Make sure to shop lines across the best sports betting apps and leverage available sportsbook promotions to get the most out of these best college basketball bets today.

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All Odds as of 6:00 a.m. ET on Nov. 24